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  Osteoporosis Medicines: Bisphosphonates
  Depending on your needs, your healthcare provider may prescribe medicines to prevent or treat osteoporosis. 
  
    Bisphosphonates
    Several medicines make up the class of bisphosphonates. They are the most common type of medicine used to help prevent and treat bone loss. Bisphosphonates are taken as a pill. Or they are injected through an IV (intravenous) infusion. They must be taken exactly as directed. They may help: 
    
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Reduce bone loss
       
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Increase bone density in the hip and spine 
       
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Reduce risk of fractures in the spine, hip, and wrist 
       
    
    Side effects may include:
    
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Heartburn
       
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Nausea
       
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Belly (abdominal) pain
       
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Bone or muscle pain
       
    
   
  
    Taking bisphosphonates pills
    
    Always read medicine information closely. You should not take bisphosphonates if you currently have upper gastrointestinal disease. Certain bisphosphonates must be taken: 
    
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On an empty stomach
       
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With a full glass of water (8 oz.) first thing in the morning on an empty stomach. 
       
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At least 30 minutes to 1 hour before any food, drink, or other medicines 
       
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While you are upright, either sitting or standing. You should not lie down for at least 30 minutes after taking the medicine to prevent esophageal irritation 
       
    
    Newer medicines can be taken weekly or monthly. Talk with your healthcare provider to find out which one is right for you.  
   
 
				
			 
			
				
				
				
				
				
						Online Medical Reviewer:
						Marianne Fraser MSN RN
						
					
						
Online Medical Reviewer:
						Raymond Turley Jr PA-C
						
					
						
Online Medical Reviewer:
						Vinita Wadhawan Researcher
						
					
				
			
					Date Last Reviewed:
					12/1/2024
					
				
		
				
				
			
					© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.